摘要：目的 观察芬太尼骨架型透皮贴剂(多瑞吉)治疗晚期肺癌中、重度疼痛的疗效.方法 42例晚期肺癌患者,治疗前均为中、重度疼痛,给予多瑞吉镇痛治疗,每24小时评定疼痛强度、生活质量、不良反应.结果 疼痛完全缓解12例(28.6%),明显缓解27例(64.3%),总有效率92.9%,患者生活质量明显改善,不良反应发生率低,主要为恶心、呕吐、嗜睡、便秘等.结论 多瑞吉治疗晚期肺癌中、重度疼痛效果良好. Abstract： Objective To observe the the efficacy of fentanyl patches (duragesic) in the treatment of advanced lung cancer with moderate to severe pain.Methods Forty-two cases of advanced lung cancer before treatment were of moderate to severe pain,who were given duragesic analgesic treatment.To assessed pain intensity, quality of life and adverse reactions every 24 hours.Results The pain complete relief in 12 cases (28.6%), 27 cases were obvious relief (64.3%). The total effective rate was 92.9%. Patients with significant improvement in the quality of life, a lower incidence of adverse reactions, mainly include nausea, vomiting, drowsiness and constipation.Conclusions Durogesic in the treatment of advanced lung cancer with moderate to severe pain has good efficacy.

关键词：芬太尼 骨架型 透皮贴剂 镇痛治疗 晚期肺癌 

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