摘要：目的 观察开胸手术后吗啡复合氯诺昔康静脉镇痛与单独应用吗啡效果比较.方法 将ASAⅠ～Ⅱ级60例择期开胸手术患者随机分为吗啡(A)组(n=30)和吗啡+氯诺昔康(B)组(n=30),A组采用吗啡60 mg+恩丹西酮4 mg,B组采用吗啡40 mg+氯诺昔康32 mg+恩丹西酮4 mg,均以生理盐水稀释至100 ml,给予吗啡2.5 mg+恩丹西酮4 mg作为负荷量后连接PCIA泵进行自控镇痛.术后第1、2、3天静息及咳嗽时行VAS评分,监测用药量及不良反应发生情况.结果 两组VAS评分比较差异无统计学意义,用药量、不良反应A组明显高于B组.结论 吗啡与氯诺昔康联合应用于开胸手术后镇痛与吗啡单独应用效果相当,但吗啡用量及不良反应发生率明显降低,是一种更安全、有效的镇痛方法. Abstract： Objective To compare the effect of morphine combined with lornoxicam and morphine alone for postoperative thoracotomy patients. Methods All 60 postoperative thoracotomy patients with ASAⅠ-Ⅱ stage were randomly divided into group A(30 cases)and group B(30 cases).All patients were given morphine and ondansetron as loading dose and then connected PCIA pump for controlled intravenous analgesia,but lornoxicam were added to the patients in group B. VAS score,drug consumption and adverse reactions were marked after operation. Results VAS score had no significant difference between the two groups,but the drug consumption and adverse reactions of group A were significant higher than that in group B. Conclusions For postoperative thoracotomy patients,taking morphine combined with lornoxicam can relieve pain effectively and meanwhile cut down drug consumption and adverse reactions.

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