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胃癌术后肠内营养支持的临床研究

吕新远 张谢夫 赵春临 L(U) Xin-yuan Xie-fu Chun-lin 中国实用医刊 2010年第08期

摘要:目的 探讨胃癌术后早期肠内营养支持的临床意义,并观察肠内营养对胃肠功能恢复、营养状况以及免疫功能的影响.方法 将40例行远端胃大部切除胃癌患者随机分为两组,20例术后行肠外营养治疗(PN组),20例术后早期行肠内营养治疗(EN组).PN组术后每日行完全肠外营养支持直到经口进食;EN组术后第1天以静脉支持为主,第2天开始经鼻营养管滴入肠内营养制剂,逐步加大用量并减少静脉支持.观察两组术后排气、排便时间,并发症发生率,平均住院费用、住院时间.结果 EN组术后排气、排便时间,并发症发生率和平均住院时间、费用均少于PN组.结论 胃癌术后早期EN支持可促进小肠功能恢复,提高免疫力,减少住院时间.肠内营养是胃癌术后营养支持的首选途径. Abstract: Objective To investigate the clinical significance of early enteral nutrition support after operation of gastric cancer.The recovery of gastrointestinal function,nutritional status and immune function were observed. Methods Forty patients with distal subtotal gastrectomy were randomly divided into two groups, 20 patients received parenteral nutrition(PN group), 20 patients were supplied with early enteral nutrition(EN group).Patients of parenteral nutrition(PN) were given total parenteral nutritional supports as routinely from the first postoperative day until oral feeding.Patients with enteral nutrition(EN) were given parenteral nutritional supports routinely on the 1st postoperative day,and then with nutrition through naso-duodenal infusion, gradually increasing the dosage and reducing the venous support.The observation indexes including flatus and defecation time,complication rate,the average hospital costs and duration.Results The time of flatus and of bowel movement, complication rate,hospital duration and costs after operation in the EN group was lower than that of the PN group.Conclusions Early postoperative enteral nutrition support can promote the recovery

关键词:胃癌术后早期肠内营养支持临床研究gastriccancer

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