摘要：目的 分析机械通气患者撤机失败原因,总结相关撤机成功经验,提高脱机成功率.方法 对本院ICU 收住的58 例机械通气脱机失败患者的临床资料进行回顾性分析.结果 58例中共有81例次撤机失败,其中自主呼吸试验失败73例次(90.1%),其具体表现为神经系统的控制问题8例次(9.6%), 呼吸系统问题52例次(71.2%),心血管系统问题9例次(13.7%),心理障碍6例次(5.5%).8例拔管后48 h内再次插管,其中3例系因原发疾病加重,2例拔管过于激进,1例发生脑卒中昏迷致无法自主咳痰,1例发生严重谵妄.治疗原发病,采用合理的撤机策略,55例(94.8%)患者实现成功撤机,3例患者未能实现撤机,2例放弃治疗,1例患者原发病恶化而死亡.结论 机械通气撤机失败的原因多样.机械通气患者脱机时应在积极治疗患者原发病的情况下,采用合适的撤机策略;脱机后亦应及时评估患者呼吸状况. Abstract： Objective Analyzing the causes of weaning failure and summarizing related weaning strategies in intensive care unit (ICU), to promote the rate of weaning success. Methods The information of 58 patients suffering from weaning failure in ICU were investigated. Results Eighty-one unsuccessful weaning cases in all patients happened,including 73 cases of failured spontaneous breathing trial.The causes of failured spontaneous breathing trial were as follows, the question of nervous system accounted for 9.6% (8 cases), too large respiratory load for 71.2% (52 cases),insufficient function of circulation system for 13.7% (9 cases),and psychologic obstacle for 5.5%(6 cases).Eight patients were reintubated 48 hours after extubation because of aggravated primary disease,radical extubation,insufficient ablity of expectoration and severe delirium.By treating primary disease and adopting proper weaning strategies,55 patients weaned sucessfully.In 3 patients who could not wean from mechanical ventilation finally,2 were because of giving up treatment,another died of p

关键词：icu 机械通气撤机 失败原因分析 对策 intensive 

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